Biomedicine

Abstract

Introduction: The emergence of pyogenic bacteria during or following trauma, burn injuries, and surgical interventions can lead to inflammation and the development of pus. An enormous financial burden, prolonged hospital stays, and considerable morbidity are the outcomes of wound infections Objective: The objective of the current study is to determine the aerobic bacteria that cause wound infections and to determine the antibiotic susceptibility pattern of the isolated organisms. Materials and methods: A retrospective study was conducted at SVS Medical College and Hospital Mahabubnagar from October 2023 to August 2024. Pus samples were aseptically collected and processed aseptically. Identification and antibiotic susceptibility pattern were done by the Vitek 2 compact system following standard procedures. Results: Out of 536 pus samples, 115 samples showed bacterial growth. Most of the bacterial growth were isolated from 21-40 years of age with 41 (36%). Among 115 bacterial isolates, 62(54%) were Gram-positive cocci and 53 (46%) were gram-negative bacilli. Among gram-positive cocci, the highest isolated organism is Staphylococcus aureus with 26 (42%). In gram-negative bacilli, the most common organism isolated is Enterobacter spp. 13 (24.5%) followed by Pseudomonas spp. with 11 (20.8%). 96% of the Staphylococcus aureus were sensitive to Linezolid and the least sensitivity was observed with Levofloxacin with 17.3%. Conclusion: The pyogenic wound infections were discovered to be common in the tertiary care hospital with staphylococcus aureus isolated and exhibiting the highest occurrence followed by Enterobacter and Pseudomonas spp. When putting empirical treatment options for pyogenic infections into practice, the susceptibility statistics from this article might be worth taking into account.