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Biomedicine

Current Issue

  • Open Access
  • Original Article

Impact of Vitamin D3 Supplementation on Health-Related Quality of Life in Women with Primary Dysmenorrhea and Vitamin D Deficiency: A Secondary Analysis

Sarita Goyal1, Kanchan Kalra1*, Meenakshi B Chauhan2

2026, 46(3), 260-266, 10.51248/v46i3.62, July 2, 2026

Background: Primary dysmenorrhea (PD) is widely prevalent gynaecological disorder that substantially impairs health-related quality of life (HRQoL). While studies have demonstrated a relationship between Vitamin D deficiency and heightened menstrual pain, there is limited eviden…

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  • Open Access
  • Original Article

Morphometric study of Infraorbital foramen in relation to inferior orbital margin in dry adult human skulls in North India

Fatima Begum1*, Manik Sehgal2, Rubinder Kaur3

2026, 46(3), 255-259, 10.51248/v46i3.60, Sept. 25, 2026

Background & Aim: Situated on the anterior maxilla, the infraorbital foramen (IOF) serves as the conduit for the infraorbital neurovascular pathway. Safe execution of regional maxillofacial blocks and invasive midface surgical approaches depends on accurate geographical anat…

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  • Open Access
  • Original Article

Implementation of Project-Based Learning (PtBL) as a Teaching–Learning Tool in Pharmacology for Phase II MBBS Students at a Medical College in Northeast India: A Prospective Interventional Study

Gautam Sahu1, Sahid Aziz1*, Ashish P. Anjankar2

2026, 46(3), 248-254, 10.51248/v46i3.47, Sept. 17, 2026

Background: Implementation of CBME has brought a paradigm shift in medical education. PtBL is an innovative teaching-learning method that encourages students to learn and apply knowledge, skills through an engaging experience.
Objectives: To implement PtBL as teaching&nda…

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  • Open Access
  • Original Article

Study of Serum Lactate Dehydrogenase, Alkaline Phosphatase and β - hCG in Women with Palpable Breast Lesions – A Cross-Sectional Study

Nongmaithem Sushantana1, Raajkumari Vidyabati Devi1*

2026, 46(3), 240-247, 10.51248/v46i3.61, Sept. 17, 2026

BACKGROUND: Globally, breast cancer ranks 2nd in cancer incidence. Both benign lesions and cancers present as lumps. Early detection of cancer is vital for treatment; there is need for a simple, sensitive method to detect tumours early.
OBJECTIVES: This s…

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  • Open Access
  • Original Article

Zein-Based Zinc Oxide Nanoparticles for Metformin Encapsulation: Synthesis, Characterization, and Biological Applications.

Santosh Mallikarjun Bhavi1, Rekha R2., Naveen M. V2., Sushmitha Mavinkar2, Pavithra R2., Chandrakala S2., Bothe Thokchom1, Akshata Choudhari Padti1, Sapam Riches Singh1, Ramesh Babu Yarajarla1, B. S. Srinath2

2026, 46(3), 227-239, 10.51248/v46i3.70, Sept. 17, 2026

Introduction and Aim: Type 2 diabetes mellitus (T2DM) remains a major global health challenge requiring improved drug delivery strategies. Zein, a maize-derived biopolymer, has attracted attention as a drug carrier because of its biocompatibility and controlled-release propertie…

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  • Open Access
  • Original Article

A Cross-Sectional Three-Year Retrospective Survey on Acute Febrile Illness in Chennai.

Vasanth Mohandass1, Ravi Kiran1, Divya Sankaramourthy1, Roshan Raj2, Lakshmi Priya Navaneethakrishnan2, Yamini Gopi1, Santhosh Rajakumar1, Bhavyaa Lakshmi Sole1, Anupama Cherayi padinakara1, Kaveri Krishnasamy1*

2026, 46(3), 213-226, 10.51248/v46i3.180, Sept. 27, 2026

Background: Acute Febrile Illness (AFI), marked by nonspecific symptoms such as fever, myalgia, and arthralgia, is difficult to diagnose due to overlapping causes like Dengue, Chikungunya, Scrub typhus, and Leptospirosis. Limited diagnostic capacity often leads to delayed or ina…

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  • Open Access
  • Original Article

Serum Magnesium Levels in Hospitalised and Outpatient Populations: A Cross-Sectional Observational Study.

Annavarapu Umalakshmi¹, Mangala N*. Sirsikar1, Shailaja Alapaty1

2026, 46(3), 204-212, 10.51248/v46i3.27, Aug. 5, 2026

Background: Magnesium is the second most abundant intracellular cation and an essential cofactor for over 600 enzymatic reactions. Dysmagnesaemia, particularly hypomagnesaemia, is a frequently underrecognised electrolyte abnormality in hospitalised patients despite its significa…

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  • Open Access
  • Original Article

Exploring the potential therapeutic mechanism of Bauhinia variegata and Commiphora wightii against colorectal cancer through network pharmacology and docking.

Jagan Muniyandi 1, Lakshmi Sankaranarayanan1, Vinoth Vengadesan1, Sadras Sudha Rani1*

2026, 46(3), 190-203, 10.51248/v46i3.32, Aug. 5, 2026

Insights on the mechanism of colorectal cancer (CRC) development and progression is critical for accurate diagnosis and better treatment. A comprehensive understanding of traditional medicines may contribute to the development of advanced therapeutic approaches. The kanchanara-guggulu (KG) formu…

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  • Open Access
  • Original Article

Association of Ki-67 Proliferation Index with Histopathological Differentiation in Locally Advanced Head and Neck Squamous Cell Carcinoma

Abhishek Soni1*, Ashok Chauhan1, Baljit Singh¹, Prateek Jangra2, Paramjeet Kaur1, Rajeev Atri1, Rakesh Dhankhar1

2026, 46(3), 183-189, 10.51248/v46i3.39, Aug. 5, 2026

INTRODUCTION: Ki-67 is a well known marker of cellular proliferation. Its clinico-pathological importance in locally advanced head and neck squamous cell carcinoma (LAHNSCC) is not clearly defined. METHODS: This prospective, observational study included histopat…

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  • Open Access
  • Review Article

Extracellular Vesicle Biomarkers in Systemic Lupus Erythematosus and Lupus Nephritis: Emerging Roles in Pathogenesis, Biomarker Development, and Clinical Translation

Aarti Verma¹*, Vineeta Batra1, Jayanand2

2026, 46(3), 171-182, 10.51248/v46i3.82, Sept. 25, 2026

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease characterized by loss of immune tolerance, autoantibody production, immune-complex deposition, and persistent inflammation. Lupus nephritis (LN) is a serious manifestation of SLE, affecting approximately 40–60% of pat…

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  • Open Access
  • Review Article

From Deficiency to Recovery: Vitamin D’s Role in Diabetic Foot Ulcers

Muzamil Bashir1, Abid Ashraf 2, Binish Gulzar3,Omar Naushad4

2026, 46(3), 163-170, 10.51248/v46i3.53, Oct. 2, 2026

Background: Diabetic foot ulcers (DFUs) are among the most serious complications of diabetes mellitus, affecting up to one-third of patients during their lifetime. They are a leading cause of hospitalization, infection, and lower-limb amputation. Emerging evidence suggests that …

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