2026, 46(3), 260-266, 10.51248/v46i3.62, July 2, 2026
Background: Primary dysmenorrhea (PD) is widely prevalent gynaecological disorder that substantially impairs health-related quality of life (HRQoL). While studies have demonstrated a relationship between Vitamin D deficiency and heightened menstrual pain, there is limited eviden…
2026, 46(3), 255-259, 10.51248/v46i3.60, Sept. 25, 2026
Background & Aim: Situated on the anterior maxilla, the infraorbital foramen (IOF) serves as the conduit for the infraorbital neurovascular pathway. Safe execution of regional maxillofacial blocks and invasive midface surgical approaches depends on accurate geographical anat…
2026, 46(3), 248-254, 10.51248/v46i3.47, Sept. 17, 2026
Background: Implementation of CBME has brought a paradigm shift in medical education. PtBL is an innovative teaching-learning method that encourages students to learn and apply knowledge, skills through an engaging experience.
Objectives: To implement PtBL as teaching&nda…
2026, 46(3), 240-247, 10.51248/v46i3.61, Sept. 17, 2026
BACKGROUND: Globally, breast cancer ranks 2nd in cancer incidence. Both benign lesions and cancers present as lumps. Early detection of cancer is vital for treatment; there is need for a simple, sensitive method to detect tumours early.
OBJECTIVES: This s…
2026, 46(3), 227-239, 10.51248/v46i3.70, Sept. 17, 2026
Introduction and Aim: Type 2 diabetes mellitus (T2DM) remains a major global health challenge requiring improved drug delivery strategies. Zein, a maize-derived biopolymer, has attracted attention as a drug carrier because of its biocompatibility and controlled-release propertie…
2026, 46(3), 213-226, 10.51248/v46i3.180, Sept. 27, 2026
Background: Acute Febrile Illness (AFI), marked by nonspecific symptoms such as fever, myalgia, and arthralgia, is difficult to diagnose due to overlapping causes like Dengue, Chikungunya, Scrub typhus, and Leptospirosis. Limited diagnostic capacity often leads to delayed or ina…
2026, 46(3), 204-212, 10.51248/v46i3.27, Aug. 5, 2026
Background: Magnesium is the second most abundant intracellular cation and an essential cofactor for over 600 enzymatic reactions. Dysmagnesaemia, particularly hypomagnesaemia, is a frequently underrecognised electrolyte abnormality in hospitalised patients despite its significa…
2026, 46(3), 190-203, 10.51248/v46i3.32, Aug. 5, 2026
Insights on the mechanism of colorectal cancer (CRC) development and progression is critical for accurate diagnosis and better treatment. A comprehensive understanding of traditional medicines may contribute to the development of advanced therapeutic approaches. The kanchanara-guggulu (KG) formu…
2026, 46(3), 183-189, 10.51248/v46i3.39, Aug. 5, 2026
INTRODUCTION: Ki-67 is a well known marker of cellular proliferation. Its clinico-pathological importance in locally advanced head and neck squamous cell carcinoma (LAHNSCC) is not clearly defined. METHODS: This prospective, observational study included histopat…
2026, 46(3), 171-182, 10.51248/v46i3.82, Sept. 25, 2026
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease characterized by loss of immune tolerance, autoantibody production, immune-complex deposition, and persistent inflammation. Lupus nephritis (LN) is a serious manifestation of SLE, affecting approximately 40–60% of pat…
2026, 46(3), 163-170, 10.51248/v46i3.53, Oct. 2, 2026
Background: Diabetic foot ulcers (DFUs) are among the most serious complications of diabetes mellitus, affecting up to one-third of patients during their lifetime. They are a leading cause of hospitalization, infection, and lower-limb amputation. Emerging evidence suggests that …